Síndrome de lise tumoral espontânea em paciente com diagnóstico de câncer de cólon metastático
Resumo
Introdução: a síndrome de lise tumoral (slt) é uma emergência oncológica metabólica que
acarreta maior risco de morbimortalidade. Está associado ao tratamento quimioterápico de doenças
neoplásicas, sendo comum em pacientes com neoplasias hematológicas malignas após o início do manejo sistêmico. No entanto, também pode ocorrer de forma espontânea ou em tumores sólidos. Apresentação do caso: apresentamos o caso de um paciente com adenocarcinoma de cólon metastático que apresentou uma síndrome de lise tumoral espontânea, relevante pela manifestação “espontânea”, sem tratamento citotóxico, em um tumor não hematológico e de forma oligossintomática. Conclusões: a síndrome de lise tumoral espontânea associada a neoplasia sólida é uma emergência oncológica rara, mas é essencial reconhecê-la, pois gera alterações metabólicas, como: hiperuricemia,
hiperfosfatemia, hipocalcemia, hipercalemia e lesão renal, o que requere manejo agressivo para evitar morbimortalidade.
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