Síndrome de lisis tumoral espontáneo en paciente con diagnóstico de cáncer de colon metastásico
Resumen
Introducción: el síndrome de lisis tumoral (slt) es una urgencia oncológica metabólica que conlleva mayor riesgo de morbimortalidad; está asociado al tratamiento con quimioterapia de enfermedades neoplásicas, es frecuente en pacientes con neoplasias hematológicas malignas tras el inicio del manejo sistémico; sin embargo, también puede presentarse de forma espontánea o en tumores sólidos. Presentación del caso: presentamos el caso de un paciente con diagnóstico de adenocarcinoma de colon metastásico, que presentó un síndrome de lisis tumoral espontáneo, de interés particular por su presentación clínica de forma “espontánea” en ausencia de tratamiento citotóxico, en un tumor no hematológico y además de manera oligosintomática. Conclusiones: el síndrome de lisis tumoral espontáneo asociado a neoplasia sólida constituye una urgencia oncológica de presentación poco frecuente, sin embargo, es necesario conocerlo, pues desarrolla alteraciones metabólicas como: hiperuricemia, hiperfosfatemia, hipocalcemia, hiperkalemia y lesión renal, que requieren manejo agresivo con el fin de evitar morbimortalidad.
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